Skip to main content
Posted 20 July, 2026

Bioinformatics Pipeline Test Engineer

Yantran LLC
Irvine, CA, US Full Time

Job Description

Experience: 2+ Years of exp Hire Type (FTE/Contract): 6 Months Must Have: Bioinformatics OR Genomics NGS OR "Next Generation Sequencing" VCF OR BAM OR FASTQ Python Testing OR QA OR "Quality Engineer" OR Validation Git Job Description: Role Overview We are seeking a Bioinformatics Test Engineer to validate and ensure the quality of NGS data pipelines and bioinformatics workflows. The role requires a strong blend of bioinformatics knowledge, QA expertise, and automation skills. Key Responsibilities Design and execute testing strategies for NGS pipelines (alignment, variant calling, annotation) Perform data validation, regression testing, and discrepancy analysis Develop automated test scripts (Python) Translate requirements into test cases and validation criteria Work with CI/CD pipelines and cloud-based workflows Collaborate with cross-functional teams to ensure data accuracy and reliability Required Skills Strong understanding of NGS workflows (FASTQ, BAM, VCF) Experience in bioinformatics pipeline testing or QA Proficiency in Python scripting Hands-on with Git and CI/CD tools Experience with cloud platforms (AWS/GCP/Azure) and data pipelines Strong problem-solving and communication skills Preferred Experience in biotech/life sciences domain Familiarity with Nextflow, Snakemake, or similar workflows Exposure to regulated environments (CLIA/FDA) What We’re Looking For Strong testing mindset + hands-on engineering skills Ability to debug pipelines and explain thought process clearly Experience with real-world data workflows (not just academic projects) Mentions NGS pipelines + testing together Has Python + Git + CI/CD Mentions variant calling / VCF validation Worked on cloud or production pipelines Reject or deprioritize if: Only academic bioinformatics (no testing/QA) Only statistics validation (no system testing) No Python or automation No infra experience (cloud / CI/CD / DB) Only local scripts, no real pipelines Other High Priority Keywords Variant Calling Pipeline Testing Regression Testing Test Strategy OR Test Case Design Data Validation Golden Dataset OR Reference Dataset CI/CD OR "GitHub Actions" OR GitLab OR "Azure DevOps" AWS OR S3 OR Cloud Nextflow OR Snakemake OR WDL OR Cromwell Automation Testing