Biologist
Job Description
Key Responsibilities:
This position will impact projects by expressing, purifying, and characterizing multispecific biologics.
Responsible for expression, purification, and remediation of multispecific biologics.
Characterize multispecific biologics (SEC, LC/MS, DSF, SDS-PAGE, endotoxin).
Utilize automation (e.g. Hamilton, AssayMap, Kingfisher) in biologics discovery processes.
Coordinate sample handoffs and aliquoting as necessary to enable timely delivery of material to cross-functional teams.
Qualifications
BS or MS in biology or related field with 2+ years (BS), or 0+ years (MS) of pharmaceutical and/or relevant experience.
Experience with protein and biologics expression, purification, and characterization.
Knowledge of analytical techniques to characterize proteins (e.g. SEC, MS, DSF).
Excellent organizational skills to track multiple requests and sample deliveries to ensure timely material delivery.
Familiarity with report generation and electronic notebook systems.
Skilled in usage of software programs, including MS Excel, Powerpoint, Word.
Excellent communication skills to convey results of experiments and plan next steps.
Protein purification and remediation (antibodies and fragments thereof)
Experience with sequence analysis tools (Vector NTI, Geneious, Genedata)
Team player with excellent verbal and written communication skills
Basic protein and biologics experience and knowledge of best practices in protein production.
Familiar with a multitude of purification resins and techniques, AKTAs, and protein QC.
Experience with sequence analysis software and automation.
Preferred Qualifications:
Experience with multispecific biologics.
Hands-on with analytical techniques including SEC, MS, endotoxin measurement, and DSF.
Hands-on experience with SEC, HIC, IEX purification of complex biologics utilizing AKTA platforms.
Experience with automation (e.g. Tecan, Hamilton, etc).
Experience with antibody engineering, design, and optimization.
Benefits:
Healthcare Insurance: Synectics offers eligible employees and their dependents healthcare coverage through BlueCross BlueShield of Illinois. Eligibility begins on the 1st day of the calendar month following 60 days of continuous full time employment with Synectics. Premiums are subsidized by Synectics.
Dental Insurance: Synectics offers eligible employees and their dependents a dental plan through MetLife. Eligibility begins on the 1st day of the calendar month following 60 days of continuous full time employment with Synectics.
Vision Insurance: Synectics offers eligible employees vision insurance through VSP. Eligibility begins on the 1st day of the calendar month following 60 days of continuous full time employment with Synectics.
401(k) Plan: The Synectics Inc. Investment Savings Retirement Plan. Synectics offers all employees who are 21 years of age or older the opportunity to invest in the 401(k) Plan on the first of the month following at least 1 calendar year after employment begins.
Synectics is an equal opportunity employer.
