Scientist
Job Description
Job description
The Biologics CMC Developability team is responsible for- (1) the identification of biophysical- and chemical liabilities in discovery-stage biologic drug candidates to guide lead selection, and (2) for characterization of the key CMC attributes important for biologic drug development.
We have an exciting opportunity for a motivated scientist to join the Biologics CMC Developability team.
Perform in-depth LC-MS based characterization of therapeutic biologic molecules and their post-translational modifications.
Conduct liquid chromatography-based characterization of biologic drug candidates (size exclusion, ion exchange, and reverse phase).
Execute experimental protocols, collect results, and perform data analysis carefully and independently.
Maintain excellent documentation of work including electronic lab notebook and protocols.
Prepare and deliver concise scientific presentations of experimental results.
Oversee maintenance of key laboratory equipment and routine laboratory operations.
Build strong relationships with other team members and across groups.
Understand and adhere to corporate standards regarding code of conduct, safety, and documentation compliance.
Qualifications:
BS or MS in Biochemistry, Biology, Chemistry (or equivalent, e.g., Chemical Engineering, Pharmaceutical Sciences) with 3-5 (BS) or 1-2 years (MS), or Ph.D. with 0+ years of biopharmaceutical industry experience.
Hands-on experience with protein mass-spectrometry (subunit analysis, peptide mapping, disulfide mapping) and data processing is required.
Experience with liquid chromatography methods commonly used for characterization of biologic proteins is required.
Experience with liquid handling robots and their programming would be highly beneficial.
Demonstrated track record of independent thinking, creativity, and scientific accomplishment.
Highly responsible and self-motivated. Skills to plan and conduct experiments with high quality and timely deliverables. Able to perform data analysis using MS Excel & GraphPad.
Team player with excellent collaboration and communication skills.
Biologics characterization using liquid chromatography- mass spectrometry (LC-MS).
Liquid chromatography methods (size-exclusion chromatography, ion exchange, reverse-phase)
Benefits:
Healthcare Insurance: Synectics offers eligible employees and their dependents healthcare coverage through BlueCross BlueShield of Illinois. Eligibility begins on the 1st day of the calendar month following 60 days of continuous full time employment with Synectics. Premiums are subsidized by Synectics.
Dental Insurance: Synectics offers eligible employees and their dependents a dental plan through MetLife. Eligibility begins on the 1st day of the calendar month following 60 days of continuous full time employment with Synectics.
Vision Insurance: Synectics offers eligible employees vision insurance through VSP. Eligibility begins on the 1st day of the calendar month following 60 days of continuous full time employment with Synectics.
401(k) Plan: The Synectics Inc. Investment Savings Retirement Plan. Synectics offers all employees who are 21 years of age or older the opportunity to invest in the 401(k) Plan on the first of the month following at least 1 calendar year after employment begins.
Synectics is an equal opportunity employer.
